Warning signs of eosinophilic esophagitis in adults and children

Warning signs of eosinophilic esophagitis in adults and children

To understand eosinophilic esophagitis, one must first comprehend the meaning of two important terms: esophagus and eosinophils. The esophagus is the tube connecting the mouth to the stomach. Eosinophils are the white blood cells in the digestive system that defend the body against allergies and parasites. Eosinophilic esophagitis (also called EoE) results from an atypical immune response within the digestive tract, which increases the number of eosinophils in the esophagus’ inner lining.

Warning signs in adults

Difficulty swallowing (dysphagia)
Difficulty swallowing, or dysphagia, is a hallmark symptom of the condition. Patients, both children and adults, may feel like food is stuck in their esophagus, making swallowing uncomfortable and challenging. This symptom often leads to delayed or impaired passage of food through the esophagus.

Food impaction
Eosinophilic esophagitis can sometimes lead to food impaction. This symptom is characterized by difficulty and discomfort as food gets lodged in the esophagus after swallowing. Food impaction can result in fullness, chest discomfort, and the need for expert intervention to remove the impacted food.

Centrally located chest pain
Centrally located chest pain that does not respond to home remedies is another distinctive symptom in adults. This pain is usually intense and can be attributed to inflammation and structural changes in the esophagus. Immediate attention is essential when individuals encounter chest pain, particularly if the pain is accompanied by shortness of breath or pain in the jaw or arm. A combination of these symptoms may indicate a heart attack.

Regurgitation or reflux
Regurgitation, characterized by the backflow of undigested food, is another common symptom in adults. When the esophagus does not function properly, the food from the stomach travels upward into the esophagus. This causes discomfort and sometimes a sour taste in the mouth. Regurgitation usually does not improve, even with general treatments or home remedies.

Heartburn
Heartburn is more common in gastroesophageal reflux disease (GERD). However, some individuals with eosinophilic esophagitis may also experience a burning sensation in the chest.

Difficulty breathing or talking
Some patients may experience respiratory symptoms, such as breathing issues, coughing, or wheezing. These discomforts can be associated with the inflammation in the esophagus.

Warning signs in children

Difficulty feeding (in infants)
Infants with eosinophilic esophagitis may exhibit signs of discomfort or resistance during feeding. As a result, the process can become challenging for both the infant and the caregiver. Recognizing and addressing feeding difficulties is crucial to prevent the condition from worsening or leading to other health issues.

Difficulty eating
As children with eosinophilic esophagitis grow older, they continue to face difficulty with eating. Sometimes, the problem may even get worse. Kids may experience discomfort or pain while swallowing dense, dry, or solid foods, impacting their overall nutritional intake and quality of life.

Decreased appetite
Esophageal inflammation can lead to sensations of obstruction and pain while swallowing, contributing to a decreased appetite. The reluctance to eat may also result from the fear of triggering symptoms like dysphagia or food impaction.

Vomiting
Vomiting is a prevalent symptom in pediatric cases. Children with the condition may vomit in response to the challenges associated with swallowing and food impaction or the discomfort caused by inflammation in the esophagus. A healthcare expert should evaluate patients who experience persistent or recurrent vomiting.

Food aversion
Children with eosinophilic esophagitis may develop aversions to certain textures or types of food due to the challenges and discomfort associated with eating.

Abdominal pain
Abdominal pain is a common complaint among children with this health condition. The inflammation in the esophagus can lead to discomfort that extends to the abdominal region. Therefore, it is vital to identify and address abdominal pain early on.

No response to GERD treatment
Some children with eosinophilic esophagitis may not respond to the treatments used for managing GERD.

Stunted growth
In severe cases, the condition can contribute to stunted growth and malnutrition in children. Early diagnosis and intervention are crucial in such cases. An expert can address the underlying causes of the problem and implement effective strategies to promote growth and overall health in affected children.

What causes eosinophilic esophagitis?
Eosinophilic esophagitis is a chronic immune-mediated inflammatory condition. It can occur when the body has a severe allergic reaction. Genetic predisposition or environmental factors can also increase one’s risk. Other triggers include certain foods (with a notable association with allergic conditions), extreme cold or dry climate, and the presence of respiratory and allergic diseases like asthma, hay fever, eczema, or atopic dermatitis. Age or gender can also be notable risk factors, with males and adults being more susceptible. Those in the high-risk group should watch for the symptoms and follow the preventive measures recommended by an expert.

When to consult a healthcare professional?
Those who experience severe or recurring symptoms of eosinophilic esophagitis should schedule an appointment with a healthcare provider. If someone regularly uses treatments for heartburn (more than twice a week), they should consult a healthcare professional to assess and address any underlying concerns.

Diagnosing and managing eosinophilic esophagitis requires a multidisciplinary approach. It may involve undergoing tests like endoscopy and biopsy and collaboration with gastroenterologists, allergists, and nutritionists. Patients may also have to make food and lifestyle modifications and monitor the condition to alleviate its symptoms and prevent complications.

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Foods to Eat and Avoid for Optimal Kidney Health

Kidneys help filter waste from the blood and dispose of it off the body via urine. They also help balance the electrolyte and fluid levels in the body. But, conditions like high blood pressure and diabetes may intervene with their ability to work as required. Furthermore, damage to the kidney might also result in chronic kidney disease. Hence making changes in your meal plan is a vital aspect of treatment. You can prevent damage to these organs by following a kidney-healthy meal plan. Below, we will address some foods to eat and avoid for better kidney health. Foods to eat Cauliflower Cauliflower is a nutritious vegetable. It's an excellent source of folate, Vitamins B, K, and C. It's rich in anti-inflammatory compounds like indoles, a fiber source. In addition, you can use mashed cauliflower as a replacement for potatoes. For example, a cup of cooked cauliflower has 40 mg of phosphorous, 176 mg of potassium, and 19 mg of sodium. Sweet potatoes They are relatively similar to white potatoes but have more fiber content, resulting in them breaking down more gradually. Hence, you will experience a less spike in insulin levels. Sweet potatoes are also rich in vitamins and minerals like potassium that help balance the sodium levels in the body and lower their impact on the kidneys. But, since sweet potatoes have a high potassium content, people on dialysis or those with CKD should curtail the intake of this vegetable. Red bell peppers They are rich in flavor and low in potassium, but that is not the sole reason they are considered a hit among people with kidney disease. Red bell peppers have Vitamin C and A sources and are also high in fiber, folic acid, and B6 vitamin content. In addition, red bell peppers are also suitable because they have lycopene, an antioxidant that shields against some cancers. You can eat them raw with a dip, mix them into your salad, or enjoy them as an appetizer. Some people also like roasting bell peppers and using them as a topping for lettuce salads or sandwiches. Olive oil It contains healthy fat and has anti-inflammatory properties. Since it is monosaturated fat, it stays stable even at higher temperatures as you cook. Thus, switching to extra virgin olive oil can give you more antioxidants while you still enjoy your favorite dish. Green vegetables Leafy veggies like spinach, kale, romaine, arugula, and cabbage are hydrating, low in calories, and have high antioxidant and vitamin content. If you wish to be cautious about your mineral levels, you must opt for cabbage and arugula, which are nutrient-rich and lower in sodium, potassium, phosphorous, and calcium. In addition, kale and spinach have a high potassium content, which is ok for people seeking to improve their kidney health, but best for those already dealing with chronic kidney disease. Blueberries They are called superfoods because they are rich in antioxidants and are a low-calorie Vitamin-C and fiber source. You can stock them in abundance from your local grocery store or farmer’s market. You can also shop for frozen berries in the off-season and enjoy healthy smoothies. People with kidney diseases can also eat other berries like raspberries, cranberries, and strawberries. Apples Apples are low in potassium and rich in fiber when you eat them with peel. They also have a natural anti-inflammatory effect and are ideal for your kidneys. Foods to avoid Soda Soda has zero nutritional benefits and instead has high sugar content. It only adds to the extra calories. Some studies link high soda consumption to conditions like kidney disease, osteoporosis, dental problems, and metabolic syndrome. If you opt for their lower calorie alternative like coke zero, even that will do you no good, as it has no nutritional value and contains artificial sweeteners and additives. Hence, you must omit soda and opt for healthy beverages like water. If you do not enjoy plain water, add a slice or two of fresh fruit for added flavor. Avocados Avocadoes are known for their many nutritious qualities. They are rich in antioxidants, fiber, and heart-healthy fats. Even though consuming avocado is often considered healthy, people with kidney disease must avoid it as avocados have a high potassium content. An average-sized avocado has about 690 mg of potassium. If you love the taste and do not want to eliminate it, you can reduce the portion size to only 1/4th of the avocado. In addition, it will lower potassium intake.  Salty foods Sodium or salt is one of the most prevalent inclusions in foods you consume daily. However, their density is higher in processed foods. Salt results in water retention and may cause blood pressure, lung, and heart disease. Healthy kidneys work towards maintaining the correct fluid balance in the body. So, if your kidneys do not function as desired, the fluid balance may be disturbed. Hence, you must curtail sodium-rich foods like processed foods, packaged items, and soy sauce. When cooking meals at home, opt for low-sodium alternatives. You can replace salt with spices and herbs and keep the salt shaker off the table. Dairy Dairy products like yogurt, cheese, ice cream, and milk are rich in protein, calcium, and other vital nutrients. They also contain potassium and phosphorous. People with stage three kidney disease might want to curtail their potassium, phosphorous, and protein intake, which is high in dairy. So, you can instead reach out for dairy alternatives like rice, soy, or almond milk as they have lower potassium, phosphorous, and protein content than cow’s milk. Bananas Though naturally low in sodium, bananas' potassium content is significantly high. So, to ensure your kidney disease does not aggravate, monitor your potassium intake, and it might be challenging if the banana is your staple. Conclusion Whatever you eat or drink will affect your health regardless of any health issue. Therefore, maintaining a healthy weight and following a balanced meal plan are prerequisites to staying fit and controlling blood sugar levels. A kidney-healthy meal plan is less about eliminating certain foods but following portion control and finding a balance of proteins, carbohydrates, and fats.

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9 warning signs of narcolepsy

Narcolepsy refers to a chronic neurological disorder in which the brain is unable to control the body’s sleep-wake cycles. Consequently, individuals with this condition typically feel energized immediately after waking up but feel lethargic throughout the day. Although narcolepsy does not lead to serious health conditions in the long run, it can impact one’s daily functioning significantly. So, here are some signs of narcolepsy one shouldn’t ignore: Warning signs of narcolepsy 1. Excessive sleepiness throughout the day A brain chemical known as hypocretin or orexin typically controls one’s sense of wakefulness. However, patients with narcolepsy are deficient in hypocretin. This deficiency is believed to be caused by the immune system’s attack on the cells that produce this brain chemical or the receptors that enable its functioning in the body. Consequently, the onset of narcolepsy leads to excessive sleepiness throughout the day despite a good night’s sleep. 2. Sleep paralysis Sleep paralysis is when one experiences loss of speech and movement while falling asleep or upon waking up. Although it lasts for a few seconds or minutes, sleep paralysis can be debilitating. This symptom is not experienced by all individuals with narcolepsy but may be a sign of the disorder and should not be ignored. 3. Fluctuations in REM sleep Rapid Eye Movement (REM) sleep is the initial stage of sleep, wherein one’s eyes move rapidly in different directions while the individual is asleep. This sleep stage is indispensable to ensure the brain’s optimal consolidation of memories during sleep and the development of the central nervous system. It is also the stage in which most individuals experience dreams. Although most individuals enter the REM stage 60-90 minutes after falling asleep, patients with narcolepsy enter REM prematurely, typically within 15 minutes. Such fluctuations in REM sleep result from changes in brain activity. 4. Unexplained loss of muscle tone The sudden loss of muscle tone, also called cataplexy, is a characteristic feature of narcolepsy and is usually caused by extreme emotional outbursts, such as intense laughter, anger outbursts, excitement, and fear. In these cases, the patient’s head may drop involuntarily, or knees may weaken, leading to a fall. 5. Obstructive sleep apnea Obstructive Sleep Apnea (OSA) involves complete or partial blockage of the airways, triggering severe breathing difficulties and nonrestorative sleep, a state in which one does not feel adequately refreshed regardless of the number of hours one may have slept. Many individuals with narcolepsy simultaneously experience obstructive sleep apnea. Consequently, patients with the latter condition may be experiencing narcolepsy and should consult a doctor. 6. Hallucinations Sleep paralysis, a common sign of narcolepsy, may cause one to experience hallucinations. However, these hallucinations may also occur among patients with narcolepsy who do not have sleep paralysis. Some examples of such hallucinations include feeling the presence of a stranger in one’s room or perceiving objects or stimuli that are not present. Hallucinations can be extremely distressing and may be a sign of narcolepsy, although they may also indicate the onset of some other neurological disorder. In any case, timely consultation with a psychiatrist is necessary. 7. Involuntary sleep while engaging in an activity Patients with narcolepsy may often fall asleep engaging in a regular activity, such as eating, working, driving, or even talking. Such involuntary sleep patterns may be risky when engaging in an activity such as driving or riding, requiring undivided attention. Such sleep is typically nonrestorative, meaning that one feels refreshed only briefly before beginning to feel drowsy again. 8. Loss of appetite Hypocretin deficiency, a prevalent symptom of narcolepsy, often leads to loss of appetite, causing one to eat much less than usual. 9. Muscle mass accumulation Despite grappling with loss of appetite (as mentioned above), many patients with narcolepsy may gain muscle mass rapidly, also resulting from a lack of hypocretin, which controls not only wakefulness but also hunger. Consequently, despite eating less, patients with narcolepsy may experience a lack of brown fat, responsible for burning calories, due to hypocretin deficiency. Lifestyle tips for patients with narcolepsy 1. Avoid caffeine, especially after sunset Individuals with narcolepsy are prone to lethargy and excess sleepiness throughout the day. Caffeine intake, particularly after sunset, can cause problems with falling asleep on time at night, worsening drowsiness during the day, and worsening narcolepsy symptoms. 2. Stay physically active Studies have shown that exercising daily for at least four to five hours before bedtime enhances sleep quality. It can also prevent patients with narcolepsy from gaining excess muscle mass. Hence, cardio activities like walking, running, jogging, cycling, swimming, and other workouts like strength training can considerably help manage narcolepsy symptoms. 3. Take planned naps Planned naps are among the best ways to manage daytime sleepiness, a common narcolepsy sign. Patients with narcolepsy should ideally schedule their naps for midmorning or early afternoon, resting in a quiet, comfortable place and setting an alarm to avoid oversleeping. 4. Regulate work shift hours Patients with narcolepsy are susceptible to fatigue and lethargy, which can affect their productivity. Hence, it is a good idea to speak with one’s supervisor and regulate work hours, working in a focused way for fewer hours than working long hours under stressful conditions. For instance, switching to six-hour shifts instead of ten hours can help manage work while ensuring optimal rest.

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